Definitions from Wiktionary (Lipinski's rule of five)
▸ noun: (chemistry) A rule of thumb stating that a chemical compound is likely to be an orally active drug in humans unless it violates more than one of these criteria: (i) no more than 5 hydrogen bond donors (the total number of nitrogen–hydrogen and oxygen–hydrogen bonds); (ii) no more than 10 hydrogen bond acceptors (all nitrogen or oxygen atoms); (iii) a molecular mass less than 500 daltons; (iv) an octanol-water partition coefficient (log P) that does not exceed 5.
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▸ noun: (chemistry) A rule of thumb stating that a chemical compound is likely to be an orally active drug in humans unless it violates more than one of these criteria: (i) no more than 5 hydrogen bond donors (the total number of nitrogen–hydrogen and oxygen–hydrogen bonds); (ii) no more than 10 hydrogen bond acceptors (all nitrogen or oxygen atoms); (iii) a molecular mass less than 500 daltons; (iv) an octanol-water partition coefficient (log P) that does not exceed 5.
▸ Words similar to Lipinski's rule of five
▸ Usage examples for Lipinski's rule of five
▸ Idioms related to Lipinski's rule of five
▸ Wikipedia articles (New!)
▸ Words that often appear near Lipinski's rule of five
▸ Rhymes of Lipinski's rule of five
▸ Invented words related to Lipinski's rule of five