Usually means: River and island in South Carolina.
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We found 7 dictionaries that define the word Edisto:

General (7 matching dictionaries)
  1. Edisto: Merriam-Webster
  2. Edisto: American Heritage Dictionary of the English Language
  3. Edisto: Wordnik
  4. Edisto: Dictionary.com
  5. Edisto: Wikipedia, the Free Encyclopedia
  6. Edisto: TheFreeDictionary.com
  7. Edisto: Wiktionary

Definitions from Wiktionary (Edisto)

noun:  (historical) A subtribe of the now-extinct Cusabo, a Native American tribal group who lived in what is now South Carolina.
noun:  One of South Carolina's Sea Islands, the larger part of which lies in Charleston County, with its southern tip in Colleton County.
noun:  A free-flowing blackwater river in South Carolina, flowing from its sources in Saluda and Edgefield counties, to its Atlantic Ocean mouth at Edisto Beach.
noun:  An unincorporated community and census-designated place in Orangeburg County, South Carolina, United States.
noun:  (historical) A member of the Native American subtribe of South Carolina.

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