Usually means: Depressions or low points geographically.
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We found 21 dictionaries that define the word Down's:

General (13 matching dictionaries)
  1. Down's, Downs, downs: Merriam-Webster
  2. downs, the Downs: Oxford Learner's Dictionaries
  3. Downs: American Heritage Dictionary of the English Language
  4. downs, the Downs: Collins English Dictionary
  5. Downs, downs: Vocabulary.com
  6. Down's, Downs, down's, downs: Wordnik
  7. downs: Cambridge Advanced Learner's Dictionary
  8. Down's, Downs, downs: Wiktionary
  9. downs, the downs: Dictionary.com
  10. downs: Cambridge Essential American English Dictionary
  11. Downs (nautical), Downs (surname), Downs, The Downs (Bristol), The Downs (ship anchorage), The Downs: Wikipedia, the Free Encyclopedia
  12. Downs: Rhymezone
  13. Downs, The Downs: TheFreeDictionary.com

Business (1 matching dictionary)
  1. Downs, The Downs: Legal dictionary

Computing (1 matching dictionary)
  1. Down's, Downs, The Downs: Encyclopedia

Medicine (2 matching dictionaries)
  1. Downs: Merriam-Webster Medical Dictionary
  2. Down's, Downs, The Downs: Medical dictionary

Miscellaneous (1 matching dictionary)
  1. Downs: Idioms

Slang (2 matching dictionaries)
  1. downs: Green’s Dictionary of Slang
  2. Downs, the downs: Urban Dictionary

Sports (1 matching dictionary)
  1. Downs: Sports Definitions

(Note: See down as well.)

Definitions from Wiktionary (Down's)

noun:  (informal) Ellipsis of Down's syndrome.

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