Sorry, no online dictionaries contain the exact phrase unapproved drug use.
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Reverse dictionary results:
1. abuse
2. addiction
3. addictions
4. explosion
5. oxycodone
6. doping
7. cocaine
8. dope
9. drugs
10. vehicle
11. narcotics
12. substance
13. investigational
14. habituation
15. idu
16. prescribe
17. controlled substance
18. abused
19. addicts
20. analeptic
21. consumer
22. consumption
23. dependence
24. exhaust
25. flash
26. homeopathy
27. idus
28. intake
29. jag
30. ketamine
31. medicine
32. prescribed
33. tranquilize
34. withdrawal
35. cook up
36. spacy
37. withdrawer
38. cross-tolerance
39. phenylpropanolamine
40. counterculture

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You can look up the words in the phrase individually using these links:   unapproved ?   drug ?   use ?
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unap*to search for words beginning with unap, or
* useto search for words ending with use
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