Sorry, no online dictionaries contain the exact phrase to make one sad.
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Reverse dictionary results:
1. depress
2. distress
3. sadden
4. grieve
5. upset
6. downtrodden
7. suffer
8. afflict
9. burthensome
10. crestfallen
11. down in the dumps
12. down in the mouth
13. exasperate
14. fraught
15. hagridden
16. hassle
17. lumbago
18. oppressed
19. plight
20. sickerly
21. ween
22. worst
23. aggravated
24. agonizing
25. ailing
26. bedevilment
27. bother
28. botheration
29. bothering
30. bummed
31. chastened
32. cripplingly
33. depressible
34. despite
35. dismay
36. dismayed
37. distraught

You can look up the words in the phrase individually using these links:   to ?   make ?   one ?   sad ?
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