Sorry, no online dictionaries contain the exact phrase respond best.
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Reverse dictionary results:
1. respond favorably
 2. react optimally
3. engage effectively
4. reply best
5. answer most positively
6. give
7. raise
8. see
9. selection
10. set
 11. support
12. hot
13. accept
14. accepted
15. accepting
16. accommodate
17. adapt
18. address
19. amenable
20. answer
 21. answering
22. assist
23. attend
24. bite
25. bow
26. bridle
27. bridled
28. capture
29. catch
30. clap
 31. competent
32. confront
33. echo
34. face
35. feedback
36. get
37. here
38. meet
39. memory
40. overreact

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