Usually means: Surgical severing of brain connections.
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We found 9 dictionaries that define the word prefrontal leukotomy:

General (6 matching dictionaries)
  1. prefrontal leukotomy: Vocabulary.com
  2. prefrontal leukotomy: Dictionary.com
  3. prefrontal leukotomy: Rhymezone
  4. prefrontal leukotomy: FreeDictionary.org
  5. prefrontal leukotomy: Mnemonic Dictionary
  6. prefrontal leukotomy: TheFreeDictionary.com

Computing (1 matching dictionary)
  1. prefrontal leukotomy: Encyclopedia

Medicine (2 matching dictionaries)
  1. prefrontal leukotomy: Merriam-Webster Medical Dictionary
  2. online medical dictionary (No longer online)

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Definitions from WordNet (prefrontal leukotomy)

▸ noun:  surgical interruption of nerve tracts to and from the frontal lobe of the brain; often results in marked cognitive and personality changes


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