Sorry, no online dictionaries contain the exact phrase opposite of uplifting.
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Reverse dictionary results:
1. ecstasy
2. elevation
3. bra
4. hoist
5. ode
6. yeast
7. against
8. back
9. bak
10. bid
11. boost
12. elevate
13. nack
14. oppose
15. opposed
16. opposing
17. put
18. recurved
19. rise
20. supine
21. tory
22. daunting
23. demoralizing
24. dispiriting
25. frustrating
26. intimidating
27. acclivous
28. accommodation
29. advance
30. advancement
31. advancing
32. along
33. antiperistaltic
34. antrorse
35. appreciate
36. appreciated
37. appreciating
38. banns
39. book fair
40. bookfair

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