Sorry, no online dictionaries contain the exact phrase opposite of reassure.
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Reverse dictionary results:
1. alarm
2. unsettle
3. agitate
4. disturb
5. worry
6. commote
7. disturbance
8. upset
9. befuddle
10. bewilder
11. boggle
12. bouleversement
13. confound
14. confuse
15. convolute
16. discombobulate
17. disconcert
18. perplex
19. pose
20. puzzle
21. turbulence
22. turmoil
23. upsetting
24. baffle
25. bamboozle
26. bemuse
27. disorient
28. distraction
29. dumbfound
30. fuddle
31. mystify
32. nonplus
33. perturb
34. pother
35. take aback
36. trouble
37. ambushed
38. bedevil
39. contrist

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You can look up the words in the phrase individually using these links:   opposite ?   of ?   reassure ?
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