Sorry, no online dictionaries contain the exact phrase opposite of profitability.
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Reverse dictionary results:
1. unprofitability
 2. loss
3. deficit
4. negative return
5. non-profitability
6. defectiveness
7. scarcity
8. weakness
9. dearth
10. defect
 11. defectibility
12. defectible
13. defective
14. deficience
15. deficiency
16. deficient
17. insufficient
18. lack
19. lacke
20. low
 21. short
22. shortage
23. subaverage
24. underexercised
25. underhanded
26. deprivation
27. disempowerment
28. disoccupation
29. inanition
30. inferiority
 31. insufficience
32. insufficiency
33. limitation
34. neglect
35. obsolescence
36. privation
37. saciety
38. sales resistance
39. security

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