Sorry, no online dictionaries contain the exact phrase opposite of painless.
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Reverse dictionary results:
1. painful
2. uncomfortable
3. agonizing
4. excruciating
5. torturous
6. affliction
7. anguished
8. anguishing
9. badly
10. bereaved
11. bewailment
12. broken-hearted
13. brokenhearted
14. crushing
15. direfully
16. disheartening
17. dismal
18. distressful
19. distressing
20. dolefull
21. dolor
22. downheartedly
23. grief
24. grief-stricken
25. griefe
26. griefful
27. grieved
28. grieving
29. grievous
30. harmfully
31. harrowing
32. heart-rending
33. heartache
34. heartbreaker
35. heartbreaking
36. heartbroken
37. heartrending
38. heartsick

You can look up the words in the phrase individually using these links:   opposite ?   of ?   painless ?
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oppo*to search for words beginning with oppo, or
*lessto search for words ending with less
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