Sorry, no online dictionaries contain the exact phrase opposite of giggle.
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Reverse dictionary results:
1. react
2. laugh
3. tee-hee
4. titter
5. tittering
6. twitter
7. tee
8. cry
9. abracadabra
10. afterpiece
11. burlesque
12. chip
13. dummy
14. fleer
15. force
16. forces
17. incongruous
18. jolly
19. ludicrous
20. mobo
21. mono
22. shill
23. skit
24. smil
25. smile
26. stratagem
27. add
28. ball
29. weep
30. ban
31. bubbly
32. funny
33. happy
34. kidding
35. mixing
36. mole
37. parody
38. sham
39. silly
40. squeak

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You can look up the words in the phrase individually using these links:   opposite ?   of ?   giggle ?
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Not helpful? You might try using the wildcards * and ? to find the word you're looking for. For example, use
oppo*to search for words beginning with oppo, or
*ggleto search for words ending with ggle
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