Sorry, no online dictionaries contain the exact phrase opposite of facile.
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Reverse dictionary results:
1. difficult
2. complex
3. challenging
4. intricate
5. arduous
6. effortful
7. intense
8. laboriously
9. laboured
10. mountainously
11. painstaking
12. toughly
13. worky
14. acutely
15. cruciately
16. daunting
17. demanding
18. difficultly
19. laboredly
20. laborious
21. laborously
22. laboursome
23. lichtly
24. ponderous
25. prolixious
26. warm
27. burdensomely
28. difficile
29. exhaustingly
30. grindingly
31. heavily
32. labor-intensive
33. labored
34. laborsome
35. low-pitched
36. moliminous
37. oldly
38. sternly

You can look up the words in the phrase individually using these links:   opposite ?   of ?   facile ?
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oppo*to search for words beginning with oppo, or
*cileto search for words ending with cile
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