Sorry, no online dictionaries contain the exact phrase opposite of close up.
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Reverse dictionary results:
1. inset
 2. near
3. shut
4. down
5. off
6. iff
7. pff
8. eye
9. far
10. eyes
 11. closing
12. thicken
13. stop
14. around
15. clam
16. closed
17. seal
18. thickened
19. crest
20. dam
 21. nestle
22. reverse
23. chock
24. barricade
25. bung
26. button
27. farm
28. shot
29. stops
30. almost
 31. barricades
32. block
33. board
34. brick
35. clams
36. closely
37. closer
38. conclude
39. end
40. fill

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You can look up the words in the phrase individually using these links:   opposite ?   of ?   close ?   up ?
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Not helpful? You might try using the wildcards * and ? to find the word you're looking for. For example, use
oppo*to search for words beginning with oppo, or
*e upto search for words ending with e up
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