Sorry, no online dictionaries contain the exact phrase opposite of anguish.
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Reverse dictionary results:
1. relief
2. comfort
3. contentment
4. joy
5. pleasure
6. comforting
7. consolator
8. comfort letter
9. consolate
10. consolatio
11. console
12. recomfort
13. solace
14. cherishment
15. comf
16. comfort zone
17. comfortable
18. comforter
19. condolence
20. condolences
21. consolation
22. consolatory
23. consoler
24. consoling
25. creature comfort
26. cushy
27. ease
28. easie
29. eazy
30. reassuring
31. solacing
32. aspiration
33. comfortability
34. comfortableness
35. comfy
36. commiserate
37. comodo
38. consolement
39. easeful

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You can look up the words in the phrase individually using these links:   opposite ?   of ?   anguish ?
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