Sorry, no online dictionaries contain the exact phrase make less refined.
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Reverse dictionary results:
1. coarsen
2. unrefine
3. debase
4. cheapen
5. demean
6. allay
7. depauperate
8. handicap
9. pauper
10. abase
11. abaser
12. abjection
13. avale
14. defile
15. deflower
16. degenerate
17. degrade
18. depreciate
19. depress
20. derogate
21. deteriorate
22. devalue
23. downgrade
24. embase
25. impair
26. impoverish
27. pair
28. pejorate
29. pluto
30. abater
31. abject
32. adaw
33. appair
34. compound
35. debaser
36. debauch
37. debellate
38. decay

You can look up the words in the phrase individually using these links:   make ?   less ?   refined ?
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