Sorry, no online dictionaries contain the exact phrase lock oneself up.
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Reverse dictionary results:
1. imprison
 2. confine
3. seclude
4. isolate
5. enclose
6. downzone
7. niche
8. closure
9. tract
10. incarcerate
 11. intestine
12. spin-off
13. clausure
14. close in
15. constrain
16. coop up
17. enrace
18. inlayer
19. occupied
20. shut away
 21. siege
22. teen
23. close
24. coarctate
25. leaguer
26. restrain
27. shut in
28. shut up
29. underpinning
30. assiege
 31. ensconce
32. furnish
33. include
34. intrusion
35. remove
36. staker
37. subduce
38. subduction
39. cubbyhole

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You can look up the words in the phrase individually using these links:   lock ?   oneself ?   up ?
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lock*to search for words beginning with lock, or
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