Sorry, no online dictionaries contain the exact phrase lessen in effect.
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Reverse dictionary results:
1. dampen
 2. blunt
3. break
4. damp
5. counteract
6. damped
7. damping
8. derogate
9. extenuate
10. palliate
 11. soften
12. softened
13. weaken
14. afraid
15. fear
16. attenuate
17. attenuated
18. bate
19. blur
20. buff
 21. check
22. cushion
23. cut
24. cuts
25. dall
26. damage
27. demoralize
28. derogatory
29. dilute
30. fall
 31. falls
32. hold
33. impair
34. impaired
35. invalidate
36. mince
37. minced
38. moderate
39. roll
40. shorten

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You can look up the words in the phrase individually using these links:   lessen ?   in ?   effect ?
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