Usually means: Protect or defend from harm.
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We found 10 dictionaries that define the word guard against:

General (8 matching dictionaries)
  1. guard against: Merriam-Webster
  2. guard against: Oxford Learner's Dictionaries
  3. guard against: Wiktionary
  4. guard against: Dictionary.com
  5. guard against: TheFreeDictionary.com
  6. guard against: Longman Dictionary of Contemporary English

Business (1 matching dictionary)
  1. guard against: Legal dictionary

Miscellaneous (1 matching dictionary)
  1. guard against: Idioms

Definitions from Wiktionary (guard against)

verb:  (transitive) To prevent something unpleasant from happening.

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