Sorry, no online dictionaries contain the exact phrase goes against the grain.
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Reverse dictionary results:
1. contradicts
2. opposes
3. conflicts
4. challenges
5. resists
6. argue
7. arguer
8. argufy
9. arguing
10. argument
11. dispute
12. moot
13. object
14. advocated
15. challenge
16. debating
17. redargue
18. allege
19. confute
20. contraindicate
21. convince
22. plead
23. protest
24. question
25. resist
26. unreason
27. arg
28. belie
29. betray
30. countermand
31. debate
32. defend
33. discoverture
34. disputation
35. forbid
36. gainsay
37. interdict
38. peach
39. quid pro quo
40. refute

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You can look up the words in the phrase individually using these links:   goes ?   against ?   the ?   grain ?
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