Sorry, no online dictionaries contain the exact phrase first line of defense.
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Reverse dictionary results:
1. frontline
2. primary defense
3. initial defense
4. first response
5. first barrier
6. van
7. bail
8. linebacker
9. base
10. prime
11. support
12. supported
13. supporting
14. trip wire
15. tower
16. octave
17. section
18. middle c
19. gap
20. acrostic
21. abatis
22. dew
23. maginot
24. orphan
25. primary
26. abattis
27. ade
28. empale
29. gapped
30. gsp
31. scrimmage
32. ballade
33. directrix
34. eldest
35. front
36. head
37. heir
38. hexameter
39. ident
40. indent

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You can look up the words in the phrase individually using these links:   first ?   line ?   of ?   defense ?
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