Usually means: Utterly frustrated, unable to solve.
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We found 4 dictionaries that define the word be at wits end:

General (1 matching dictionary)
  1. be at wits' end: TheFreeDictionary.com

Business (1 matching dictionary)
  1. be at wits' end: Legal dictionary

Computing (1 matching dictionary)
  1. be at wits' end: Encyclopedia

Miscellaneous (1 matching dictionary)
  1. be at wits' end: Idioms



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