Usually means: Major, abrupt influenza virus change.
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We found 11 dictionaries that define the word antigenic shift:

General (4 matching dictionaries)
  1. antigenic shift: Wiktionary
  2. antigenic shift: Dictionary.com
  3. Antigenic shift: Wikipedia, the Free Encyclopedia
  4. antigenic shift: TheFreeDictionary.com

Business (1 matching dictionary)
  1. antigenic shift: Legal dictionary

Computing (1 matching dictionary)
  1. antigenic shift: Encyclopedia

Medicine (5 matching dictionaries)
  1. Dorland's Illustrated Medical Dictionary (No longer online)
  2. Antigenic shift: MedTerms.com Medical Dictionary
  3. online medical dictionary (No longer online)
  4. antigenic shift: Medical dictionary
  5. Antigenic shift: Drug Medical Dictionary

Definitions from Wiktionary (antigenic shift)

noun:  The process by which different strains of a virus or viruses combine to form a new subtype having a mixture of the surface antigens of the original strains.

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