We found one dictionary that defines the word U.S. Route 66:

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1. U.S. Route 66: Encyclopedia

Phrases: U.S. Route 66 in Arizona, U.S. Route 66 in California, U.S. Bicycle Route 66, U.S. Route 66 in Illinois, U.S. Route 66 in Oklahoma, more... ▸ Words similar to U.S. Route 66 ▸ Usage examples for U.S. Route 66 ▸ Idioms related to U.S. Route 66 ▸ Wikipedia articles (New!) ▸ Words that often appear near U.S. Route 66 ▸ Rhymes of U.S. Route 66 ▸ Invented words related to U.S. Route 66