Usually means: Cancer cell with central mucin.
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We found 9 dictionaries that define the word Signet ring cell:

General (3 matching dictionaries)
  1. signet-ring cell, signet ring cell: Dictionary.com
  2. Signet-ring cell, Signet ring cell: Wikipedia, the Free Encyclopedia
  3. signet-ring cell: TheFreeDictionary.com

Business (2 matching dictionaries)
  1. signet-ring cell, Signet ring cell: Legal dictionary

Computing (1 matching dictionary)
  1. signet-ring cell: Encyclopedia

Medicine (3 matching dictionaries)
  1. signet ring cell: Merriam-Webster Medical Dictionary
  2. Dorland's Illustrated Medical Dictionary (No longer online)
  3. signet-ring cell, signet ring cell: Medical dictionary

Definitions from Wikipedia (Signet ring cell)

noun:  In histology, a signet ring cell is a cell with a large vacuole.

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