Sorry, no online dictionaries contain the exact phrase wakefulness agent.
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Reverse dictionary results:
1. vigil
2. agrypnotic
3. mesmerism
4. vigilance
5. restless
6. sleepless
7. agrypnia
8. insomnia
9. sleeplessness
10. watchful
11. alertness
12. contentment
13. darkness
14. debility
15. developmental
16. inactivity
17. mindfulness
18. nap
19. passivity
20. relaxation
21. restlessness
22. sleep
23. somnolence
24. surveillance
25. daymare
26. hypnopompic
27. intersomnious
28. absence
29. ful
30. insomniac
31. insomnolence
32. temazepam
33. tossing
34. unrest
35. unsleeping
36. vigilant
37. wakerife
38. abnormal
39. acculturative
40. arousal

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You can look up the words in the phrase individually using these links:   wakefulness ?   agent ?
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