Usually means: Cultured individuals with refined tastes.
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We found 10 dictionaries that define the word sophisticates:

General (8 matching dictionaries)
  1. sophisticates: Merriam-Webster
  2. sophisticates: Collins English Dictionary
  3. sophisticates: Vocabulary.com
  4. Sophisticates, sophisticates: Wordnik
  5. sophisticates: Cambridge Advanced Learner's Dictionary
  6. sophisticates: Wiktionary
  7. sophisticates: Dictionary.com
  8. sophisticates: TheFreeDictionary.com

Business (1 matching dictionary)
  1. sophisticates: Legal dictionary

Medicine (1 matching dictionary)
  1. sophisticates: Merriam-Webster Medical Dictionary

(Note: See sophisticate as well.)

Definitions from Wiktionary (sophisticate)

verb:  (transitive)
verb:  To make (something) less innocent or natural; to artificialize.
verb:  To make (something) more sophisticated (“complex, developed, or refined”); to develop, to refine.
verb:  (also reflexive) To make (oneself or someone) more sophisticated (“experienced in the ways of the world, that is, cosmopolitan or worldly-wise”); to cosmopolitanize.
verb:  (also figuratively) To alter and make impure (something) by mixing it with some foreign or inferior substance, especially with an intention to deceive; to adulterate; (generally) to corrupt or deceive (someone, their thinking, etc.).
verb:  To change the meaning of (something) in a deceptive or misleading way.
verb:  (archaic) To apply an artificial technique to (something).
verb:  (intransitive) To practise sophistry (“the (deliberate) making of arguments that seem plausible but are fallacious or misleading”).
adjective:  Synonym of sophisticated (adjective)
adjective:  Of a person: experienced in the ways of the world; cosmopolitan, worldly-wise.
adjective:  Of art or other things: appealing to the tastes of an intellectual or sophisticated (sense 1.1) person; cerebral; also, cultured, elegant, refined.
adjective:  (obsolete) Mixed with a foreign or inferior substance; not genuine or pure; adulterated, impure.
adjective:  (obsolete) Of a thing: having its meaning changed in a deceptive or misleading way.
noun:  A person who is sophisticated (“experienced in the ways of the world, that is, cosmopolitan or worldly-wise”), or who has sophisticated tastes.
▸ Also see sophisticate


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