Sorry, no online dictionaries contain the exact phrase single substrate.
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Reverse dictionary results:
1. attached
2. support
3. epimerase
4. hydrogenase
5. plant
6. sessile
7. bog
8. bogging
9. boh
10. chip
11. conversion
12. hybrid
13. recognize
14. channel
15. channelling
16. channels
17. drop
18. esperanto
19. fusion
20. money
21. orphan
22. orphaned
23. paper
24. pull
25. receptacle
26. side
27. sum
28. monoamine
29. skeg
30. accounting data
31. aether
32. alanine
33. anchor
34. anchoring
35. backbone
36. baculum
37. barren
38. bear
39. bear out
40. benefice

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You can look up the words in the phrase individually using these links:   single ?   substrate ?
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