Usually means: Isomers with different functional arrangements.
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We found 4 dictionaries that define the word positional isomer:

General (2 matching dictionaries)
  1. positional isomer: Wiktionary
  2. Positional isomer: Wikipedia, the Free Encyclopedia

Computing (1 matching dictionary)
  1. positional isomer: Encyclopedia

Medicine (1 matching dictionary)
  1. positional isomer: Medical dictionary

Definitions from Wiktionary (positional isomer)

noun:  (chemistry) any isomer that differs from another isomer only in the position of a substituent, or of a double or triple bond

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