Sorry, no online dictionaries contain the exact phrase main route.
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Reverse dictionary results:
1. artery
 2. highway
3. thoroughfare
4. main road
5. primary route
6. access road
7. arterial
8. arterial road
9. autoroute
10. beeline
 11. belt loop
12. beltline
13. beltway
14. broadway
15. bus lane
16. bylane
17. carpool lane
18. carriageway
19. central reservation
20. climbing lane
 21. corridor
22. diamond lane
23. divided highway
24. dogleg
25. dualling
26. express lane
27. expressway
28. expwy
29. expy
30. freeway
 31. high road
32. high street
33. interstate
34. lane
35. laned
36. loop
37. main
38. motorway

You can look up the words in the phrase individually using these links:   main ?   route ?
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main*to search for words beginning with main, or
*outeto search for words ending with oute
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