Sorry, no online dictionaries contain the exact phrase main cause.
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Reverse dictionary results:
1. primary cause
 2. root cause
3. underlying cause
4. chief cause
5. fundamental cause
6. joke
7. jokes
8. abduct
9. eddy
10. gibberellin
 11. act
12. aim
13. anchor
14. attack
15. back
16. bak
17. basis
18. board
19. bowl
20. burden
 21. causes
22. center
23. chapel
24. concentrate
25. crow
26. current
27. cuts
28. door
29. drag
30. draw
 31. drift
32. drifting
33. drop
34. dynamic
35. dynamite
36. effect
37. face
38. fever
39. flood
40. focus

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You can look up the words in the phrase individually using these links:   main ?   cause ?
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