Usually means: Large ring-shaped chemical structure.
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We found 10 dictionaries that define the word macrocyclic:

General (8 matching dictionaries)
  1. macrocyclic: Merriam-Webster
  2. macrocyclic: Oxford Learner's Dictionaries
  3. macrocyclic: Collins English Dictionary
  4. macrocyclic: Wiktionary
  5. macrocyclic: Webster's New World College Dictionary, 4th Ed.
  6. macrocyclic: Infoplease Dictionary
  7. macrocyclic: Dictionary.com
  8. Macrocyclic: Wikipedia, the Free Encyclopedia

Computing (1 matching dictionary)
  1. macrocyclic: Encyclopedia

Medicine (1 matching dictionary)
  1. macrocyclic: Merriam-Webster Medical Dictionary

Definitions from Wiktionary (macrocyclic)

adjective:  (chemistry) Of an organic compound: having a closed ring of more than about twelve atoms.
adjective:  (chemistry) Of or relating to a macrocycle.
adjective:  (mycology) Pertaining to a rust fungus whose life cycle includes all five spore stages: pycniospore (spermatium), aeciospore, urediniospore, teliospore, and basidiospore.

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