Sorry, no online dictionaries contain the exact phrase lose mastery.
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Reverse dictionary results:
1. face
2. art
3. conquer
4. dominate
5. learn
6. master
7. mastering
8. possess
9. subjugate
10. abate
11. age
12. bobble
13. bow
14. break
15. break down
16. break up
17. breakdown
18. carry
19. collapse
20. come
21. countenance
22. crack
23. default
24. disintegrate
25. disorient
26. dissolve
27. drop
28. erupt
29. flip
30. forget
31. freak
32. fumble
33. head
34. heads
35. keep
36. leave
37. loose
38. loses
39. nod
40. panic

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You can look up the words in the phrase individually using these links:   lose ?   mastery ?
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lose*to search for words beginning with lose, or
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