Sorry, no online dictionaries contain the exact phrase lose affection.
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Reverse dictionary results:
1. disaffect
 2. estrange
3. alienate
4. cool
5. heart
6. hearts
7. throw
8. win
9. confuse
10. die
 11. dir
12. dote
13. baby
14. hair
15. misplace
16. soul
17. balance
18. balancing
19. blind
20. blur
 21. blurring
22. bow
23. break
24. carry
25. choke
26. collapse
27. come
28. comedown
29. dall
30. dash
 31. dashed
32. daze
33. decay
34. decaying
35. decline
36. degenerate
37. depersonalize
38. despair
39. despond
40. deter

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You can look up the words in the phrase individually using these links:   lose ?   affection ?
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lose*to search for words beginning with lose, or
*tionto search for words ending with tion
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