Sorry, no online dictionaries contain the exact phrase informed guess.
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Reverse dictionary results:
1. hypothesis
2. speculation
3. conjecture
4. theory
5. ad hoc
6. conjecturing
7. hypothesizer
8. ipse dixit
9. propositional
10. thesis
11. a posteriori
12. ascriptive
13. generalisation
14. heuristic
15. postulating
16. ratiocinatio
17. working hypothesis
18. abductive reasoning
19. arguendo
20. assumption
21. deductive
22. deductivism
23. determinist
24. generalization
25. given
26. hypothetic
27. inference
28. inventio
29. posit
30. postulate
31. postulation
32. postulational
33. postulator
34. postulatory
35. postulatum
36. ratiocination

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