Usually means: Increase negativity of cell membrane.
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We found 9 dictionaries that define the word hyperpolarize:

General (7 matching dictionaries)
  1. hyperpolarize: Merriam-Webster
  2. hyperpolarize: American Heritage Dictionary of the English Language
  3. hyperpolarize: Collins English Dictionary
  4. hyperpolarize: Wiktionary
  5. hyperpolarize: Infoplease Dictionary
  6. hyperpolarize: Dictionary.com
  7. hyperpolarize: TheFreeDictionary.com

Medicine (2 matching dictionaries)
  1. hyperpolarize: Merriam-Webster Medical Dictionary
  2. hyperpolarize: Medical dictionary

Definitions from Wiktionary (hyperpolarize)

verb:  To increase the polarity of something, especially the polarity across a biological membrane

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