Usually means: Reduces sensitivity to specific stimuli.
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We found 10 dictionaries that define the word desensitizer:

General (7 matching dictionaries)
  1. desensitizer: Merriam-Webster
  2. desensitizer: Oxford Learner's Dictionaries
  3. desensitizer: Collins English Dictionary
  4. desensitizer: Wiktionary
  5. desensitizer: Dictionary.com
  6. Desensitizer: Wikipedia, the Free Encyclopedia
  7. desensitizer: TheFreeDictionary.com

Computing (1 matching dictionary)
  1. desensitizer: Encyclopedia

Medicine (2 matching dictionaries)
  1. desensitizer: Merriam-Webster Medical Dictionary
  2. desensitizer: Medical dictionary

(Note: See desensitize as well.)

Definitions from Wiktionary (desensitizer)

noun:  Anything that desensitizes.
noun:  Any substance applied to the non-image part of a lithographic plate so that ink will not stick to it.

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