Sorry, no online dictionaries contain the exact phrase central issue.
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Reverse dictionary results:
1. peripheral
 2. age
3. asia
4. basic
5. critical
6. crucial
7. crux
8. dispatch
9. draw
10. era
 11. essence
12. essential
13. forum
14. front
15. fundamental
16. head
17. importance
18. important
19. iran
20. item
 21. kashmir
22. key
23. nub
24. part
25. point
26. points
27. priority
28. radiate
29. radiating
30. ray
 31. side
32. speed
33. square
34. theme
35. turkey
36. upshot
37. arm
38. motive
39. term
40. chad

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