Usually means: Person with severe mental disorder.
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We found 35 dictionaries that define the word psycho:

General (26 matching dictionaries)
  1. psycho: Longman Dictionary of Contemporary English
  2. psycho, psycho-: Merriam-Webster
  3. psycho, psycho-: Oxford Learner's Dictionaries
  4. psycho, psycho-: American Heritage Dictionary of the English Language
  5. psycho, psycho-: Collins English Dictionary
  6. psycho: Vocabulary.com
  7. Psycho, psycho, psycho-: Wordnik
  8. psycho, psycho-: Cambridge Advanced Learner's Dictionary
  9. psycho, psycho-: Wiktionary
  10. psycho, psycho (psych-): The Wordsmyth English Dictionary-Thesaurus
  11. psycho: Infoplease Dictionary
  12. Psycho-, psycho, psycho-: Dictionary.com
  13. psycho, psycho-: Online Etymology Dictionary
  14. psycho: Cambridge Essential American English Dictionary
  15. Psycho (Amy Shark song), Psycho (Hitchcock film), Psycho (Imelda May song), Psycho (Muse song), Psycho (Post Malone song), Psycho (Puddle of Mudd song), Psycho (Red Velvet song), Psycho (automaton), Psycho (disambiguation), Psycho (film), Psycho (film series), Psycho (franchise), Psycho (novel), Psycho (song), Psycho (soundtrack), Psycho (wrestler), Psycho: Wikipedia, the Free Encyclopedia
  16. Psycho-: Online Plain Text English Dictionary
  17. psycho-: Webster's Revised Unabridged, 1913 Edition
  18. psycho: Rhymezone
  19. Psycho-: AllWords.com Multi-Lingual Dictionary
  20. psycho, psycho-: MyWord.info
  21. psycho, psycho-: FreeDictionary.org
  22. psycho: Mnemonic Dictionary
  23. psycho, psycho, psycho-: TheFreeDictionary.com
  24. psycho, psycho-: Webster's New World College Dictionary, 4th Ed.

Art (1 matching dictionary)
  1. psycho-: A Cross Reference of Latin and Greek Elements

Business (1 matching dictionary)
  1. MoneyGlossary.com (No longer online)

Computing (1 matching dictionary)
  1. Psycho (disambiguation), Psycho: Encyclopedia

Medicine (2 matching dictionaries)
  1. online medical dictionary (No longer online)
  2. Psycho (disambiguation), psycho, psycho-: Medical dictionary

Miscellaneous (1 matching dictionary)
  1. PSYCHO: Acronym Finder

Slang (3 matching dictionaries)
  1. psycho, psycho, psycho: Green’s Dictionary of Slang
  2. psycho: ESL Slang page
  3. Psycho, The Psycho, psycho-: Urban Dictionary

(Note: See psychos as well.)

Definitions from Wiktionary (
)
American English Definition British English Definition
adjective:  (colloquial or derogatory) Psychotic, psychopathic, or (broadly) otherwise insane.
noun:  (chiefly derogatory, slang) A person who is psychotic, psychopathic, or (broadly) otherwise insane.
noun:  (chiefly derogatory, slang, loosely) A person who acts in a bizarre or dangerous manner.
noun:  (informal) A class, at a college or university, in which psychology is taught.

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