Usually means: Brain region involved in decision-making.
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We found 4 dictionaries that define the word orbitofrontal:

General (3 matching dictionaries)
  1. orbitofrontal: Wordnik
  2. orbitofrontal: Wiktionary
  3. orbitofrontal: Dictionary.com

Medicine (1 matching dictionary)
  1. orbitofrontal: Merriam-Webster Medical Dictionary

Definitions from Wiktionary (orbitofrontal)

adjective:  Located in the frontal lobes above the orbits of the eyes.

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