Usually means: Person who predominantly uses left hand.
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We found 14 dictionaries that define the word leftie:

General (10 matching dictionaries)
  1. leftie: Longman Dictionary of Contemporary English
  2. leftie: Oxford Learner's Dictionaries
  3. leftie: Collins English Dictionary
  4. Leftie, leftie: Wordnik
  5. leftie: Cambridge Advanced Learner's Dictionary
  6. leftie: Wiktionary
  7. leftie: Infoplease Dictionary
  8. leftie: Dictionary.com
  9. Leftie: Wikipedia, the Free Encyclopedia
  10. leftie: TheFreeDictionary.com

Computing (1 matching dictionary)
  1. Leftie: Encyclopedia

Medicine (1 matching dictionary)
  1. Leftie: Medical dictionary

Slang (2 matching dictionaries)
  1. leftie: Green’s Dictionary of Slang
  2. leftie: Urban Dictionary

Definitions from Wiktionary (Leftie)

noun:  Alternative form of lefty [(Canada, US, informal) One who is left-handed.]

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