Usually means: Impair function by causing blockages.
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We found 17 dictionaries that define the word gum up:

General (13 matching dictionaries)
  1. gum up, gum up (something): Merriam-Webster
  2. gum up: Collins English Dictionary
  3. gum up: Vocabulary.com
  4. gum up: Wordnik
  5. gum up: Wiktionary
  6. gum up: Dictionary.com
  7. gum up: Rhymezone
  8. gum up: FreeDictionary.org
  9. gum up: Mnemonic Dictionary
  10. gum up: TheFreeDictionary.com
  11. gum up: Longman Dictionary of Contemporary English

Computing (1 matching dictionary)
  1. gum up: Encyclopedia

Medicine (1 matching dictionary)
  1. gum up: Medical dictionary

Miscellaneous (1 matching dictionary)
  1. gum up: Idioms

Slang (1 matching dictionary)
  1. gum up: Green’s Dictionary of Slang

Definitions from Wiktionary (gum up)

verb:  (intransitive) To become gooey or gummy.
verb:  (transitive) To cause to be gooey or gummy, especially with the effect of obstructing the operation of some mechanism or process.
verb:  (transitive, idiomatic, by extension) To make non-functional; to interfere with or put into a state of disorder; to ruin.

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