Usually means: Deceive or cheat someone unfairly.
Definitions Related words Mentions
We found 7 dictionaries that define the word screw over:

General (2 matching dictionaries)
  1. screw over: Wiktionary
  2. screw over: TheFreeDictionary.com

Computing (1 matching dictionary)
  1. screw over: Encyclopedia

Medicine (1 matching dictionary)
  1. screw over: Medical dictionary

Miscellaneous (1 matching dictionary)
  1. screw over: Idioms

Slang (2 matching dictionaries)
  1. American-Australian Slang Dictionary (No longer online)
  2. Screw over: Urban Dictionary

Definitions from Wiktionary (screw over)

verb:  (transitive, slang, mildly vulgar) To cheat someone, or ruin their chances in a game or other situation.

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