Usually means: Lacking an opening in iris.
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We found 3 dictionaries that define the word pupilless:

General (3 matching dictionaries)
  1. pupilless: Merriam-Webster
  2. pupilless: Wiktionary
  3. pupilless: Dictionary.com

Definitions from Wiktionary (pupilless)

adjective:  (of eyes) Lacking pupils.

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