Definitions from Wiktionary (lock up)

▸ verb:  (transitive) To imprison or incarcerate (someone).
▸ verb:  (transitive) To put (something) away in a locked location for safekeeping; (occasionally, chiefly humorously) to sequester (a person) in a similar way.
▸ verb:  (intransitive) To close (and often lock) all doors and windows (of a place) securely.
▸ verb:  (transitive) To lock (a door, window, etc.).
▸ verb:  (intransitive, computing) To cease responding.
▸ verb:  (transitive, computing) To cause (a program) to cease responding or to freeze.
▸ verb:  (intransitive, mechanics) To stop moving; to seize.
▸ verb:  (of a wheel) To stop spinning due to excessive braking torque.
▸ verb:  To lose one's forward momentum; to freeze.
▸ verb:  (intransitive, motor racing) To (mistakenly) cause or have one of one's wheels to lock up (stop spinning).
▸ verb:  (transitive) To invest in something long term.
▸ verb:  (intransitive, boating) To travel through a flight of locks on a waterway in an uphill direction.
▸ verb:  (obsolete, printing) To fasten quoins securely with a mallet and a shooting-stick.

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