Usually means: Partner in a romantic relationship.
Definitions Related words Mentions
We found 19 dictionaries that define the word significant other:

General (16 matching dictionaries)
  1. significant other: Longman Dictionary of Contemporary English
  2. significant other: Merriam-Webster
  3. significant other: Oxford Learner's Dictionaries
  4. significant other: American Heritage Dictionary of the English Language
  5. significant other: Collins English Dictionary
  6. significant other: Vocabulary.com
  7. significant other: Wiktionary
  8. significant other: Infoplease Dictionary
  9. significant other: Dictionary.com
  10. Significant Other (album), Significant Other (play), Significant Other, Significant other: Wikipedia, the Free Encyclopedia
  11. significant other: Rhymezone
  12. significant other: FreeDictionary.org
  13. significant other: Mnemonic Dictionary
  14. significant other: TheFreeDictionary.com

Medicine (2 matching dictionaries)
  1. significant other: Merriam-Webster Medical Dictionary
  2. Significant Other (album), significant other: Medical dictionary

Miscellaneous (1 matching dictionary)
  1. Sociology (No longer online)

(Note: See significant_others as well.)

Definitions from Wiktionary (significant other)

noun:  One's exclusive romantic partner.
noun:  A person with whom one has an important bond of some kind.

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