Usually means: Informed about; familiar with subject.
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We found 9 dictionaries that define the word up on:

General (8 matching dictionaries)
  1. up on: Oxford Learner's Dictionaries
  2. up on: Vocabulary.com
  3. up-on: Wordnik
  4. up on: Wiktionary
  5. up on: Dictionary.com
  6. up on: FreeDictionary.org
  7. up on: Mnemonic Dictionary
  8. up on: TheFreeDictionary.com

Slang (1 matching dictionary)
  1. up on: Green’s Dictionary of Slang

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Definitions from Wiktionary (up on)

▸ adjective:  (idiomatic, colloquial) Well-informed concerning.

Similar:
au courant, informed, au fait, abreast of, hot on, genned in, high, plugged in, booked up, switched on, more...

Opposite:
down on, unaware of, ignorant of

Phrases:
check up on, beat up on, pick up on, follow up on, get up on the wrong side of the bed, more...



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Similar:
au courant, informed, au fait, abreast of, hot on, genned in, high, plugged in, booked up, switched on, more...

Opposite:
down on, unaware of, ignorant of

Phrases:
check up on, beat up on, pick up on, follow up on, get up on the wrong side of the bed, read up on, take up on, checked up on, checking up on, checks up on, reading up on, reads up on, beaten up on, more...



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