Usually means: Difficulty breathing when lying down.
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We found 18 dictionaries that define the word orthopnea:

General (9 matching dictionaries)
  1. orthopnea: Vocabulary.com
  2. orthopnea: Wiktionary
  3. orthopnea: Infoplease Dictionary
  4. orthopnea: Dictionary.com
  5. Orthopnea: Wikipedia, the Free Encyclopedia
  6. orthopnea: Rhymezone
  7. orthopnea: FreeDictionary.org
  8. orthopnea: Mnemonic Dictionary
  9. orthopnea: TheFreeDictionary.com

Computing (1 matching dictionary)
  1. orthopnea: Encyclopedia

Medicine (8 matching dictionaries)
  1. orthopnea: Merriam-Webster Medical Dictionary
  2. Dorland's Illustrated Medical Dictionary (No longer online)
  3. Orthopnea: MedTerms.com Medical Dictionary
  4. Orthopnea: Merck Manuals
  5. orthopnea: Medical dictionary
  6. University of Maryland Glossary of Medical Terms (No longer online)
  7. Orthopnea: Drug Medical Dictionary
  8. Hyperdictionary (No longer online)

Definitions from Wiktionary (Orthopnea)

noun:  Alternative spelling of orthopnoea [Shortness of breath when lying flat, causing the person to have to sleep propped up in bed or sitting in a chair.]

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