Usually means: Small, furry, social rodent pets.
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We found 14 dictionaries that define the word guinea pigs:

General (8 matching dictionaries)
  1. guinea pigs: Merriam-Webster
  2. guinea pigs: Collins English Dictionary
  3. guinea pigs: Vocabulary.com
  4. Guinea-pigs, guinea-pigs: Wordnik
  5. guinea pigs: Cambridge Advanced Learner's Dictionary
  6. guinea pigs: Wiktionary
  7. Guinea Pigs, Guinea pigs: Wikipedia, the Free Encyclopedia
  8. Guinea pigs: TheFreeDictionary.com

Computing (1 matching dictionary)
  1. Guinea pigs: Encyclopedia

Medicine (4 matching dictionaries)
  1. guinea pigs: Merriam-Webster Medical Dictionary
  2. Medical Dictionary (No longer online)
  3. online medical dictionary (No longer online)
  4. Guinea pigs: Medical dictionary

Slang (1 matching dictionary)
  1. Guinea Pigs: Urban Dictionary

(Note: See guinea_pig as well.)

Definitions from Wiktionary (guinea pig)

noun:  Any tailless rodent of the genus Cavia, which have short ears and superficially resemble large hamsters.
noun:  (especially) A domestic guinea pig, Cavia porcellus, often kept as a pet.
noun:  (figuratively) A living experimental subject.
noun:  (dated, slang) A professional company director, without time or real qualifications for the duties.
noun:  (nautical, obsolete) A midshipman in the East India service; (by extension) a low-skilled or non-proficient seaman.
▸ Also see guinea_pig

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